劉培

發布者:石喬梓發布時間:2024-07-18浏覽次數:2551

職稱:副教授       E-mail:liupei@njucm.edu.cn      主要研究方向:中藥資源化學與方劑功效物質基礎研究


 

個人簡介

副教授,醫學科學博士。主要研究方向為中藥資源化學與方劑功效物質基礎研究,具體包括:(1)經典名方及其組方藥對、藥味的功效物質基礎及配伍規律研究;(2)道地藥材品質形成機制研究。入選江蘇省六大人才高峰高層次人才培養對象、江蘇省高校青藍工程優秀青年骨幹教師培養對象。主持國家自然科學基金、江蘇省自然科學基金優秀青年基金、江蘇省高校重大基礎研究計劃等科研項目近10項。作為主要貢獻者獲教育部自然科學一等獎、中華中醫藥學會科學技術一等獎、農業農村部2016-2018年度全國農牧漁業豐收獎二等獎。以第一或通訊作者發表高水平學術論文30餘篇。第一發明人獲授權發明專利4項。參編專著4部,副主編學術專著2部。

 

承擔的主要科研項目

1、國家自然科學基金面上項目,81573555,基于藥物相互作用的香附氣血藥對相使和合的組成結構與協同增效機理研究,2016/01-2019/1272萬元,主持

2、江蘇省基礎研究計劃(自然科學基金)優秀青年基金項目,BK20160097,香附四物湯幹預氣滞血瘀型痛經的代謝組學研究,2016/7-2019/650萬元,主持

3、國家自然科學基金青年基金,8120288,香附四物湯幹預氣滞血瘀證原發性痛經的功效物質基礎研究,2013/01-2015/1222萬元,已主持

4、江蘇省自然科學青年科學基金,BK2012456,香附四物湯幹預氣滞血瘀證原發性痛經的代謝組學研究,2012/07-2015/0620萬元,主持

5、江蘇省自然科學基金面上項目,BK20201403,栝樓果瓤傳統功效的物質基礎與作用機制研究,2020/07-2023/0610萬元,主持

 

代表性論文

[1] Xin Pan, Pei Liu*, Yi-Wei Wang, Yan-Ling Yi, Huang-Qin Zhang, Da-Wei Qian, Ping Xiao, Er-Xin Shang, Jin-Ao Duan*. Synthesis of starch nanoparticles with controlled morphology and various adsorption rate for urea. Food Chemistry, 2022, 369: 130882

[2] Shao-Qing Zhu, Pei Liu*, Wen-Xing Wu, Dan Li, Er-Xin Shang, Sheng Guo, Da-Wei Qian, Hui Yan, Wei Wang, Jin-Ao Duan*. Multi-constituents variation in medicinal crops processing: Investigation of nine cycles of steam-sun drying as the processing method for the rhizome of Polygonatum cyrtonema. Journal of Pharmaceutical and Biomedical Analysis, 2021, 209: 114497

[3] Wei-Meng Feng†, Pei Liu†, Hui Yan*, Sen Zhang, Er-Xin Shang, Guang Yu, Shu Jiang, Da-Wei Qian, Jun-Wei Ma and Jin-Ao Duan*. Impact of Bacillus on Phthalides Accumulation in Angelica sinensis (Oliv.) by Stoichiometry and Microbial Diversity Analysis. Frontiers in Microbiology, 2021, 11: 611143.

[4] Hui-wei Li#, Pei Liu#, Huang-qin Zhang, Wei-meng Feng, Hui Yan, Sheng Guo, Da-wei Qian, Jin-ao Duan*. Determination of bioactive compounds in the nonmedicinal parts of Scrophularia ningpoensis using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry and chemometric analysis. Journal of Separation Science, 2020, 43(22): 4191-4201.

[5] Huang-qin Zhang, Pei Liu*, Jin-ao Duan*, Ling Dong, Er-xin Shang, Da-wei Qian, Zhen-hua Zhu, Hui-wei Li, Wei-wen Li. Comparative analysis of carbohydrates, nucleosides and amino acids in different parts of Trichosanthes kirilowii Maxim. by (ultra) high-performance liquid chromatography coupled with tandem mass spectrometry and evaporative light scattering detector methods. Molecules, 2019, 24, 1440.

[6] Huang-qin Zhang, Pei Liu*, Jin-ao Duan*, Ling Dong, Er-Xin Shang, Da-wei Qian, Ping Xiao, Ming Zhao, Wei-wen Li. Hierarchical extraction and simultaneous determination of flavones and triterpenes in different parts of Trichosanthes kirilowii Maxim. by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2019, 167: 114-122.

[7] Pei Liu*, Er-xin Shang, Yue Zhu, Da-wei Qian, Jin-ao Duan*. Volatile component interaction effects on compatibility of Cyperi Rhizoma and Angelicae Sinensis Radix or Chuanxiong Rhizoma by UPLC-MS/MS and response surface analysis. Journal of Pharmaceutical and Biomedical Analysis, 2018, 160: 135-143.

[8] Pei Liu, Er-Xin Shang, Yue Zhu, Jin-Gao Yu, Da-Wei Qian, Jin-Ao Duan*. Comparative analysis of compatibility effects on invigorating blood circulation for Cyperi Rhizoma series of herb pairs using untargeted metabolomics. frontiers in Pharmacology, 2017, 8: article 677.

[9] Pei Liu, Yuan Xu, Hui Yan, Jing Chen, Er-Xin Shang, Da-Wei Qian, Shu Jiang, Jin-Ao Duan*. Characterization of molecular signature of the roots of Paeonia lactiflora during growth. Chinese Journal of Natural Medicines, 2017, 15(10):0785-0793

[10] Pei Liu, Jin-long Zhao, Jin-ao Duan*, Da-wei Qian, Sheng Guo, Yu-ping Tang. Assay of 44 compounds in the cortex and xylem from roots and branches of Ginkgo biloba L. by ultra high performance liquid chromatography coupled with tandem mass spectrometry and chemometric analysis. Journal of Separation Science, 2015, 38: 3815-3824.

 

獲得獎項與榮譽

劉培(1/3),栝樓資源的綜合利用,第七屆江蘇省“互聯網+”大學生創新創業大賽三等獎,指導老師,2021

劉培(1/2),栝樓資源循環利用的實踐,首屆江蘇省研究生“健康江蘇”創意大賽,優秀指導老師,2018

劉培(8/25),栝樓綠色高效生産關鍵技術研究與示範推廣,農業農村部2016-2018年度全國農牧漁業豐收獎(農業技術推廣成果獎)二等獎2019

劉培(8/15),代表性經典方劑類方衍化關系與功效物質研究技術體系創建及其應用,中華中醫藥學會,科學技術獎,一等獎,2016

劉培(3/16),四物湯類方治療不同證型原發性痛經的功效物質基礎與生物學機制,國家教育部,自然科學獎,一等獎,2015




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