王若甯

發布者:花文婷發布時間:2022-09-27浏覽次數:8097



職稱:教授                              E-mail:ruoningw@njucm.edu.cn         

主要研究方向:1. 仿生型智能靶向系統的設計與應用研究2. 中藥高效給藥遞送系統的設計與研究。重點圍繞惡性腫瘤、中樞神經系統疾病等重大疾病的藥遞送瓶頸,設計智能藥物載體,利用中藥活性組分特征,實現跨越病竈屏障,定位濃集給藥”


 

個人簡介

王若甯,博士,教授,碩士研究生導師,共青團bevictor伟德官网委員會副書記(兼),入選全國中醫藥青年國醫精英,江蘇省科協青年科技人才托舉工程,江蘇省“333高層次人才培養工程及中華中醫藥學會青年人才托舉工程A類)等,獲江蘇省青年顆粒學獎主持包括國家自然科學基金(面上、青年)、江蘇省自然科學基金等10項國家級省級廳局級項目。以第一作者或通訊作者在藥學、中藥學領域頂級學術期刊ACS Nano, Bioactive Materials, Small (Front cover報道), Biomaterials, Acta Pharmaceutica Sinica B, Journal of Controlled Release(4篇), Chemical Engineering Journal,Journal of Medicinal Chemistry, Theranostics, Nano Research, Journal of Nanobiotechnology等發表多篇高水平論文,其中IF>1012篇,申請并公開國家專利10項,授權7PCT 1

現任世界中醫藥學會聯合會經皮給藥專業委員會理事;國際VEBLEO協會會士;中國顆粒學會青年理事;中華中醫藥學會中藥制劑分會、中國藥理學與安全性研究分會委員;江蘇省青科協生物與醫藥科學專委會委員;江蘇省中醫藥學會藥學專委會青年委員兼職工作秘書;南京藥學會藥劑與藥理專委會委員國家自然科學基金評審專家、江蘇省科技評估中心中青年科技評審專家。任《Asian Journal of Pharmaceutical Science》《中草藥》中英雙刊、《bevictor伟德官网學報》、《中國藥科大學學報》等雜志青年編委。參編江蘇省高等學校重點教材《工業藥劑學》、《藥物制劑工程學》。

指導本科生及研究生多次獲得國家級大學生創新創業訓練計劃江蘇省研究生實踐創新計劃,并多次獲得國家獎學金。多次獲得江蘇省本科生優秀畢業設計(論文)一等獎、二等獎及優秀團隊指導教師等榮譽稱号。獲“挑戰杯”全國大學生課外學術科技作品競賽江蘇省一等獎、二等獎,江蘇省“互聯網+”大學生創新創業大賽二等獎指導教師等榮譽稱号。


代表性論文

1. Jiwei Cui, Xue Wang, Jinge Li, Anran Zhu, Yingjiang Du, Wei Zeng, Yumiao Guo, Liuqing Di, Ruoning Wang*. Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy against glioblastoma. ACS Nano, 2023, 17: 1464-1484

2. Ruoning Wang, Xiaohong Wang, Junsong Li, Liuqing Di, Jianping Zhou*, Yang Ding*. Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma. Bioactive Materials, 2022, 13: 286-299

3. Ruoning Wang, Chenshuang Zhang, Junsong Li, Jinyu Huang, Yaw Opoku-Damoah, Bo Sun, Jianping Zhou, Liuqing Di*, Yang Ding*. Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics. Biomaterials. 2019, 221: 119413

4. Ruoning Wang, Yue Han, Bo Sun, Ziqiang Zhao, Yaw Opoku-Damoah, Hao Cheng, Huaqing Zhang, Jianping Zhou*, Yang Ding*. Tumor deep penetrating bioparticulates inspired burst intracelluar drug release for precision chemo-phototherapy. Small, 2018, 14: 1703110 

5. Jiwei Cui, Yuanxin Xu, Haiyan Tu, Huacong Zhao, Honglan Wang, Liuqing Di, Ruoning Wang*. Gather wisdom to overcome barriersWell-designed nano-drug delivery systems for treating gliomas. Acta Pharmaceutica Sinica B, 2022, 12: 1100-1125

6. Ruoning Wang*, Xinru Zhang, Jianyu Huang, Kuanhan Feng, Yingjie Zhang, Jie Wu, Lei Ma, Anran Zhu, Liuqing Di*. Bio-fabricated nanodrugs with chemo-immunotherapy to inhibit glioma proliferation and recurrence. Journal of Controlled Release, 2023, 354: 572-587

7. Ruoning Wang*, Xiaohong Wang, Yuting Zhang, Huacong Zhao, Jiwei Cui, Junsong Li*, Liuqing Di*. Emerging prospects of extracellular vesicles for brain disease theranostics. Journal of Controlled Release, 2022, 341: 844-868

8. Ruoning Wang, Xiaochen Gu, Jianping Zhou*, Lingjia Shen, Lifang Yin, Peiying Hua, Yang Ding*. Green design “bioinspired disassembly-reassembly strategy” applied for improved tumor-targeted anticancer drug delivery. Journal of Controlled Release, 2016, 235: 134-146

9. Yuanxin Xu, Kuanhan Feng, Huacong Zhao, Liuqing Di*, Lei Wang*, Ruoning Wang*. Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment. Theranostics, 2022, 12: 1683-1714

10. Jie Wu‡, Lei Ma‡, Danni Sun‡, Xinru Zhang, Jiwei Cui, Yingjiang Du, Yumiao Guo, Xue Wang, LiuqingDi, Ruoning Wang*. Bioengineering extracellular vesicles as novel nanocarriers towards brain disorders. Nano Research, 2022, 1-25

11. Ruoning Wang, Yujie Yang, Mengmeng Yang, Dandan Yuan, Jinyu Huang, Rui Chen, Honglan Wang, Lihong Hu, Liuqing Di, Junsong Li*. Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions. Journal of Nanobiotechnology, 2020, 18: 116 





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