王若甯

發布者:韓婧發布時間:2024-07-18浏覽次數:2323



姓名:王若甯

職稱:教授 博士研究生導師

E-mail:ruoningw@njucm.edu.cn

主要研究方向

     腦靶向中藥制劑的研究


個人簡介

王若甯,博士,教授、博士研究生導師,博士後合作導師,校團委兼職副書記,中藥制劑系副主任,江蘇省中藥高效給藥系統工程技術研究中心行政主任。入選國家高層次青年人才計劃,全國中醫藥青年國醫精英,江蘇省優青,江蘇省“333高層次人才培養工程、江蘇省科協青年科技人才托舉工程、中華中醫藥學會青年人才托舉工程(A類),獲江蘇省青年顆粒學獎。

聚焦中藥多組分腦靶向仿生遞送系統的研究,主持國家自然科學基金(面上、青年)等國家級、省級、廳局級項目二十餘項,以第一或通訊作者發表ACS NanoJournal of Controlled Release5篇),Bioactive MaterialsActa Pharmaceutica Sinica B2篇)Nano TodayNano Letters, Small, Biomaterials , Chemical Engineering Journal等高水平論文四十餘篇,其中IF>1020篇,多篇文章入選ESI高被引及封面文章;申請并公開國家專利14項,其中授權8項,PCT 1項。

現任世界中醫藥學會聯合會經皮給藥專業委員會理事、中國顆粒學會青年理事、中華中醫藥學會中藥制劑分會委員、中藥毒理學與安全性研究分會委員等,任《Asian Journal of Pharmaceutical Sciences》、中草藥中英雙刊、《bevictor伟德官网學報》等期刊青年編委,參編江蘇省高等學校重點教材《工業藥劑學》、《中藥藥劑學》等。

指導學生獲江蘇省優秀碩士學位論文(2人次),連續五年指導本科生獲得省級優秀本科畢業論文一等獎、省級二等獎等,連續三年獲得省級優秀畢業論文團隊獎。作為第一指導教師指導學生榮獲第十八屆挑戰杯全國大學生課外學術科技作品競賽國賽二等獎、江蘇省選拔賽一等獎和二等獎,第八屆江蘇省互聯網+”大學生創新創業大賽二等獎,入選第十六屆全國大學生創新創業年會改革成果展示項目,受邀參加第十六屆全國大學創新創業年會。

 

代表性論文

1. Jiwei Cui, Xue Wang, Jinge Li, Anran Zhu, Yingjiang Du, Wei Zeng, Yumiao Guo, Liuqing Di, Ruoning Wang*.Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy against glioblastoma.ACS Nano,2023, 17: 1464-1484

2. Ruoning Wang, Xiaohong Wang, Junsong Li, Liuqing Di, Jianping Zhou*, Yang Ding*. Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma. Bioactive Materials, 2022, 13: 286-299

3. Jiale Li, Hanwen Zhang, Yingyu Jiang, Nengjin Li, Anran Zhu, Yingjie Zhang, Kuanhan Feng, Wei Zeng, Liuqing Di*, Ruoning Wang*. The landscape of extracellular vesicles combined with intranasal delivery towards brain diseases. Nano Today, 2024,55: 102169

4. Jinge Li, Xiaohong Wang, Yumiao Guo, Yingjie Zhang, Anran Zhu, Wei Zeng, Liuqing Di, Ruoning Wang*. Ginsenoside Rg3-engineered exosomes as effective delivery platform for potentiated chemotherapy and photoimmunotherapy of glioblastoma. Chemical Engineering Journal, 2023, 471: 144692

5. Jiwei Cui, Yuanxin Xu, Haiyan Tu, Huacong Zhao, Honglan Wang, Liuqing Di, Ruoning Wang*. Gather wisdom to overcome barriersWell-designed nano-drug delivery systems for treating gliomas. Acta Pharmaceutica Sinica B, 2022, 12: 1100-1125

6. Ruoning Wang*, Xue Wang, Huacong Zhao, Nengjin Li, Jiale Li, Hanwen Zhang, Liuqing Di*.Targeted delivery of hybrid nanovesicles for enhanced brain penetration to achieve synergistic therapy of glioma. Journal of Controlled Release, 2024, 365: 331-347

7. Ruoning Wang*, Xinru Zhang, Jianyu Huang, Kuanhan Feng, Yingjie Zhang, Jie Wu, Lei Ma, Anran Zhu, Liuqing Di*. Bio-fabricated nanodrugs with chemo-immunotherapy to inhibit glioma proliferation and recurrence. Journal of Controlled Release, 2023, 354: 572-587

8Ruoning Wang*, Xiaohong Wang, Yuting Zhang, Huacong Zhao, Jiwei Cui, Junsong Li*, Liuqing Di*. Emerging prospects of extracellular vesicles for brain disease theranostics. Journal of Controlled Release, 2022, 341: 844-868

9. Ruoning Wang, Chenshuang Zhang, Junsong Li, Jinyu Huang, Yaw Opoku-Damoah, Bo Sun, Jianping Zhou, Liuqing Di*, Yang Ding*. Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics. Biomaterials. 2019, 221: 119413

10. Ruoning Wang*, Jinge Li, Xiaohong Wang, Yingjie Zhang, Anran Zhu, Kuanhan Feng, Junsong Li, Liuqing Di*. Personalized nanovaccines enhance lymph node accumulation and reprogram the tumor microenvironment for improved photodynamic immunotherapy. Nano Letters, 2024, 24: 7432-7442

 




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